CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/V560D

V560D

CIViC ID: 971 · Gene: KIT

Variant Summary

Also known as
VAL560ASP,RS121913521
HGVS
ENST00000288135.5:c.1679T>A,NM_000222.2:c.1679T>A,NP_000213.1:p.Val560Asp,NC_000004.11:g.55593613T>A
Variant Type(s)
missense_variant
Evidence Items
4

Evidence Level Distribution

Level C: 1Level D: 3

Evidence Items

Showing CIViC evidence rows where gene = KIT and variant = V560D.

LevelTypeDirectionSignificanceDiseaseDrugsRating
CPredictiveSupportsResistanceGastrointestinal Stromal TumorSunitinib3
DPredictiveSupportsSensitivity/ResponseGastrointestinal Stromal TumorPonatinib,Regorafenib Anhydrous,Sunitinib,Imatinib3
DPredictiveDoes Not SupportResistanceCancerSunitinib2
DPredictiveSupportsSensitivity/ResponseCancerImatinib Mesylate2