Variant Summary
- Also known as
- RS121913521,VAL560GLY
- HGVS
- NM_000222.2:c.1679T>G,NP_000213.1:p.Val560Gly,NC_000004.11:g.55593613T>G,ENST00000288135.5:c.1679T>G
- Variant Type(s)
- missense_variant
- Evidence Items
- 2
Evidence Level Distribution
Level D: 2
Evidence Items
Showing CIViC evidence rows where gene = KIT and variant = V560G.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| D | Predictive | Supports | Sensitivity/Response | Gastrointestinal Stromal Tumor | Regorafenib Anhydrous,Ponatinib,Imatinib | 3 |
| D | Predictive | Does Not Support | Resistance | Cancer | Imatinib | 2 |