CIViC Compass
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IDH2 R140/R172 mutation

Gene: IDH2 · Type: mutation

Indications: Acute myeloid leukemia

SensitivityResistanceCIViC Context

Linked CIViC Profile: IDH2 MUTATION

Evidence Level Distribution

Level A: 1Level B: 3Level C: 1Level D: 1
LevelTypeDirectionSignificanceDiseaseDrugsRating
DPredictiveSupportsSensitivity/ResponseAcute Myeloid LeukemiaEnasidenib4
APredictiveSupportsSensitivity/ResponseAcute Myeloid LeukemiaEnasidenib4
BPrognosticSupportsBetter OutcomeChondrosarcoma4
BPrognosticDoes Not SupportAcute Myeloid Leukemia3
BPrognosticSupportsBetter OutcomeBrain Glioma3
CPredictiveSupportsSensitivity/ResponseAcute Myeloid LeukemiaVenetoclax3