CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
Home/Biomarker

KIT or PDGFRA mutation (GIST)

Gene: KIT · Type: mutation

Indications: Gastrointestinal stromal tumor

SensitivityResistanceCIViC Context

FDA Sensitivity Assertions

DrugIndicationRecommendationFDA SourceLink
ImatinibGastrointestinal stromal tumorINDICATED
FDA Label
Label
SunitinibGastrointestinal stromal tumorINDICATED
FDA Label
Label
RegorafenibGastrointestinal stromal tumorINDICATED
FDA Label
Label
RipretinibGastrointestinal stromal tumorINDICATED
FDA Label
Label