CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
Home/Biomarker

KIT or PDGFRA mutation (GIST)

Gene: KIT · Type: mutation

Indications: Gastrointestinal stromal tumor

SensitivityResistanceCIViC Context

Linked CIViC Profile: KIT MUTATION

Evidence Level Distribution

Level B: 1Level D: 1
LevelTypeDirectionSignificanceDiseaseDrugsRating
BPredictiveSupportsSensitivity/ResponseMelanomaImatinib3
DPredictiveSupportsSensitivity/ResponseGastrointestinal Stromal TumorImatinib,Pictilisib2