Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.

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MSI-H / dMMR

Gene: MMR · Type: msi

Indications: Solid tumors, Colorectal cancer

Sensitivity Resistance CIViC Context

FDA Sensitivity Assertions

Drug	Indication	Recommendation	FDA Source	Link
Pembrolizumab	Solid tumors, Colorectal cancer	INDICATED	FDA Label	Label
Dostarlimab	Solid tumors, Colorectal cancer	INDICATED	FDA Label	Label
Nivolumab	Solid tumors, Colorectal cancer	INDICATED	FDA Label	Label
Ipilimumab	Solid tumors, Colorectal cancer	INDICATED	FDA Label	Label
Lenvatinib	Solid tumors, Colorectal cancer	INDICATED	FDA Label	Label