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MYD88 L265P mutation (Waldenström's)

Gene: MYD88 · Type: mutation

Indications: Waldenström's Macroglobulinemia

SensitivityResistanceCIViC Context

Evidence Level Distribution

Level B: 2Level D: 2
LevelTypeDirectionSignificanceDiseaseDrugsRating
BPredictiveSupportsSensitivity/ResponseLymphoplasmacytic LymphomaIbrutinib4
DPredictiveSupportsResistanceBreast CancerPaclitaxel2
BPrognosticSupportsBetter OutcomeChronic Lymphocytic Leukemia2
DPredictiveSupportsSensitivity/ResponseLymphoplasmacytic LymphomaIMG-2005-5,IRAK-1/4 Inhibitor1