CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
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RET mutation (medullary thyroid cancer)

Gene: RET · Type: mutation

Indications: Thyroid cancer

SensitivityResistanceCIViC Context

Linked CIViC Profile: RET MUTATION

Evidence Level Distribution

Level A: 2Level B: 2
LevelTypeDirectionSignificanceDiseaseDrugsRating
APredictiveSupportsSensitivity/ResponseMedullary Thyroid CarcinomaSelpercatinib4
APredictiveSupportsSensitivity/ResponseMedullary Thyroid CarcinomaSelpercatinib4
BPrognosticSupportsPoor OutcomeMedullary Thyroid Carcinoma3
BPredictiveSupportsSensitivity/ResponseMedullary Thyroid CarcinomaSelpercatinib3