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TPMT / NUDT15 deficiency — thiopurine toxicity

Gene: TPMT/NUDT15 · Type: variant

Indications: Acute lymphoblastic leukemia, Solid tumors

SensitivityResistanceCIViC Context

FDA Resistance Assertions

DrugIndicationRecommendationFDA SourceLink
MercaptopurineAcute lymphoblastic leukemia, Solid tumorsNOT RECOMMENDED
FDA Label
Label
ThioguanineAcute lymphoblastic leukemia, Solid tumorsNOT RECOMMENDED
FDA Label
Label