CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.

CIViC Genes

613 genes indexed

CIViC IDGeneEntrez IDDescription
1559DTX11840
1563DUSP21844
1567DUSP61848
1590EBF11879
26599ECSCR641700
1627EFNA21943
1634EGF1950
19EGFR1956EGFR is widely recognized for its importance in cancer. Amplification and mutations have been shown to be driving events
1646EIF1AX1964
1651EIF4A11973
1655EIF4EBP11978
24374EML6400954
13556EMSY56946
1704EP3002033
1705EPAS12034
3364EPCAM4072
1650EPHA21969
1719EPHB22048
1721EPHB42050
1728EPOR2057
20ERBB22064ERBB2, commonly referred to as HER2, is amplified and/or overexpressed in 20-30% of invasive breast carcinomas. HER2-pos
1733ERBB32065
1734ERBB42066ErbB4 (HER4) is one of the four members in the EGFR subfamily of receptor tyrosine kinases. Ligands include EGF, epiregu
1735ERCC12067
1736ERCC22068ERCC2 functions as a DNA repair gene involved in separating the double helix via 5’-3’ helicase activity. It forms a par
1739ERCC32071
1740ERCC42072
1741ERCC52073
1742ERCC62074
1737EREG2069
71ERG2078
12271ERRFI154206
21ESR12099ESR1 has been a focus in breast cancer for quite some time, but is also clinically relevant in endometrial, ovarian and
1753ESR22100
1762ETS12113
1763ETS22114
1764ETV12115
1767ETV42118
1768ETV52119
1769ETV62120
54EWSR12130Fusions between EWSR1 and multiple 3` partners are regularly identified in soft tissue sarcomas and can aid in different
63EZH22146
19896FAAP20199990
1810FANCA2175
1811FANCC2176
12754FANCL55120
375FAS355
1827FAT12195
15318FBXO1180204
9443FBXW1123291
Page 4 of 13 (613 genes)