Variant Summary
- Also known as
- LYS57ASN,RS869025608
- HGVS
- NM_002755.3:c.171G>T,NP_002746.1:p.Lys57Asn,NG_008305.1:g.53245G>T,NC_000015.9:g.66727455G>T,ENST00000307102.5:c.171G>T
- Variant Type(s)
- missense_variant
- Evidence Items
- 2
Evidence Level Distribution
Level B: 1Level D: 1
Evidence Items
Showing CIViC evidence rows where gene = MAP2K1 and variant = K57N.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| B | Prognostic | Supports | Poor Outcome | Lung Adenocarcinoma | 3 | |
| D | Predictive | Supports | Sensitivity/Response | Lung Adenocarcinoma | Selumetinib | 2 |