Variant Summary
- Also known as
- Q17K,GLN79LYS,RS1057519804
- HGVS
- NC_000014.8:g.105243048G>T,NM_001014432.1:c.235C>A,NP_001014432.1:p.Gln79Lys,ENST00000407796.2:c.235C>A
- Variant Type(s)
- missense_variant
- Evidence Items
- 3
Evidence Level Distribution
Level C: 1Level D: 2
Evidence Items
Showing CIViC evidence rows where gene = AKT1 and variant = Q79K.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| D | Predictive | Supports | Resistance | Melanoma | Vemurafenib | 4 |
| C | Predictive | Supports | Resistance | Melanoma | Dabrafenib | 4 |
| D | Predictive | Supports | Resistance | Melanoma | Vemurafenib | 2 |