Variant Summary
- Also known as
- ASP407ALA
- HGVS
- NC_000010.10:g.104850745T>G,NM_012229.4:c.1220A>C,NP_036361.1:p.Asp407Ala,ENST00000343289.5:c.1220A>C
- Variant Type(s)
- missense_variant
- Evidence Items
- 2
Evidence Level Distribution
Level D: 2
Evidence Items
Showing CIViC evidence rows where gene = NT5C2 and variant = D407A.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| D | Predictive | Supports | Resistance | T-cell Acute Lymphoblastic Leukemia | Mercaptopurine,Thioguanine | 4 |
| D | Predictive | Does Not Support | Resistance | T-cell Acute Lymphoblastic Leukemia | Arabinosylguanine,Nelarabine | 4 |