CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/EXPRESSION

EXPRESSION

CIViC ID: 25 · Gene: CDK4

Variant Summary

HGVS
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Variant Type(s)
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Evidence Items
3

Evidence Level Distribution

Level D: 3

Evidence Items

Showing CIViC evidence rows where gene = CDK4 and variant = EXPRESSION.

LevelTypeDirectionSignificanceDiseaseDrugsRating
DPredictiveSupportsSensitivity/ResponseEstrogen-receptor Positive Breast CancerAlpelisib4
DPredictiveSupportsSensitivity/ResponseSarcomaPalbociclib4
DPredictiveSupportsSensitivity/ResponseChildhood B-cell Acute Lymphoblastic LeukemiaDexamethasone,Ribociclib2