Variant Summary
- HGVS
- —
- Variant Type(s)
- —
- Evidence Items
- 3
Evidence Level Distribution
Level C: 1Level D: 2
Evidence Items
Showing CIViC evidence rows where gene = NT5C2 and variant = R238W.
| Level | Type | Direction | Significance | Disease | Drugs | Rating |
|---|---|---|---|---|---|---|
| D | Predictive | Supports | Resistance | Childhood Acute Lymphocytic Leukemia | Thioguanine,Mercaptopurine | 4 |
| D | Predictive | Does Not Support | Resistance | Childhood Acute Lymphocytic Leukemia | Gemcitabine,Cytarabine,Doxorubicin,Prednisolone | 4 |
| C | Prognostic | Supports | Poor Outcome | Childhood Acute Lymphocytic Leukemia | 2 |