CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.
CIViC Variants/Loss-of-function

Loss-of-function

CIViC ID: 5081 · Gene: LRP1B

Variant Summary

HGVS
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Variant Type(s)
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Evidence Items
2

Evidence Level Distribution

Level B: 2

Evidence Items

Showing CIViC evidence rows where gene = LRP1B and variant = Loss-of-function.

LevelTypeDirectionSignificanceDiseaseDrugsRating
BPredictiveSupportsSensitivity/ResponseSolid TumorImmune Checkpoint Inhibitor3
BPredictiveSupportsSensitivity/ResponseLung AdenocarcinomaImmune Checkpoint Inhibitor3