CIViC Compass
Research use only — not FDA-cleared, not medical advice. Always consult FDA-approved labeling and a qualified clinician.

CIViC Genes

613 genes indexed

CIViC IDGeneEntrez IDDescription
7777KEAP19817
7502KIF239493
29KIT3815c-KIT activation has been shown to have oncogenic activity in gastrointestinal stromal tumors (GISTs), melanomas, lung c
8253KLF210365
7356KLF49314
634KLF5688
13880KLHL1457565
16661KLHL689857
32083KLLN100144748
3537KMT2A4297
7725KMT2B9757
14089KMT2C58508
64KMT2D8085
30KRAS3845Mutations in the RAS family of proteins are frequently observed across cancer types. The amino acid positions that accou
3215KRT183875
3236LAG33902
3274LEPR3953
6772LGR58549
12146LRP1B53353LRP1B is a putative tumor suppressor and a member of the low-density lipoprotein (LDL) receptor family. The LDL receptor
3342LTB4050
3359LYN4067
6523LZTR18216
8197MAEA10296
3389MAGEA44103
11261MAGEH128986
31MAP2K15604MAP2K1 is a dual-specificity kinase known for it's involvement in the ERK pathway by activation of ERK1 and ERK2. MAP2K1
4542MAP2K25605
5200MAP2K46416
4546MAP2K75609
3480MAP3K14214
4532MAPK15594
7084MBD48930
3448MCL14170
3465MDM24193
3466MDM44194
1771MECOM2122
33873MEF2B100271849
3475MEF2C4208
32MEF2D4209
3485MEN14221
8331MERTK10461
52MET4233Mesenchymal Epithelial Transition MET is a prototypical receptor tyrosine kinase. Its ligand is Hepatocyte Growth Factor
9427MGA23269
34MGMT4255
24929MIR21406991
24938MIR218-1407000
3527MITF4286
3529MKI674288
3532MLH14292MLH1 is a tumor suppressor gene involved in DNA mismatch repair. Germline mutations in this gene are known to cause Lync
3548MMP14312
Page 7 of 13 (613 genes)